AB0689 LIFESTYLE AND NUTRITIONAL STATUS IN ITALIAN PATIENTS WITH ISOLATED SJӦGREN’S SYNDROME

Background Dietary habits and Physical Activity (PA) are two pivotal features of healthy life in terms the prevention treatment metabolic chronic disease [1] . Few data available concerning these issues isolated Sjӧgren’s syndrome (SS) patients [2] Objectives Aim study was to assess level PA, adherence Mediterranean diet (MD) nutritional status Italian with SS. Methods Consecutive SS (AECG criteria 2002) were enrolled. For each patient ESSDAI, ESSPRI, SSDDI calculated. The value focus score obtained minor salivary gland biopsy (MSG), when performed. International Questionnaire (IPAQ) administered physical activity; Diet (MDiet) [3] employed analyse (the spans from 0 - no 55 maximum adherence). In a subgroup 26 patients, dietary evaluated daily food diary. Sarcopenia, muscle failure that accrue across lifetime, identified by diagnostic algorithm [4] age-differentiated cut-offs; Hand Grip test (HGT) Chair Stand (CST) used as screening tests, Dual Energy X-ray Absorptiometry (DEXA) confirm quantify Appendicular Skeletal Mass (ASM, kg/m 2 ). muscular performance (6-minutes Walking Test – 6MWT) measured grading sarcopenia. Statistical analysis performed SPSS. Results 130 pSS enrolled showed moderate (median MDiet = 33, third quintile) played moderately PA MET x min/wk second tertile). No significant associations found between BMI, clinimetric index (ESSDAI, SSDDI). BMI higher older (R 0.96, p 0.02). 16 out subjects (61%) reduction strength (HGT and/or CST) therefore condition probable sarcopenia but only 6 (23%) be sarcopenic (ASM). Only one had 6MWT less than 10% predicted reduced min/wk. Patients’ consisted 43% total energy coming carbohydrate, fat represented 40% intake, remaining 17% proteins. Fat consumption is complex carbohydrates intake lower compared levels nutrient for population [5] Conclusion This preliminary considering women shows MD similar what previously reported general female Europe (32.5 ± 5 DS) [6] Moreover, results subgroup, seem have an unbalanced because foods recommended Diet. A possible explanation fats may lubricating effect aiding mastication swallowing. It can hypothesized might partly responsible increasing damage associated mass. References [1]Bonofiglio, Nutrients 2022 [2]Ng, Rheumatol Int, 2017 [3]Panagiotakos, J Med Food, 2007 [4]Cruz-Jentoft, 2019 [5]LARN 2014 [6]Fallazize, 2018 Acknowledgements: NIL. Disclosure Interests None Declared.